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Methods Multiple mouse models, including diethylnitrosamine (DEN)-induced and Trp53KO/C-MycOE-induced HCC models, mouse hepatoma cell and human HCC cell xenograft models with subcutaneous or orthotopic injection were used

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Clinical Evidence Review (2025 Update) The clinical landscape of GHK-Cu has matured since the early 2000s, with several peer-reviewed human studies now confirming moderate but measurable benefits

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